Please use this identifier to cite or link to this item:
Title: Patients' perceptions of health-related quality of life during and after adjuvant radiotherapy for T1N0M0 breast cancer
Authors: Sundaresan, Puma
Sullivan, L.
Pendlebury, S.
Kirby, A.
Rodger, A.
Joseph, D.
Campbell, I.
Dhillon, H.M.
Stockler, M.R.
Keywords: Cancer;Radiotherapy
Year: Jan-2015
Citation: Volume 27, Issue 1, pp. 9 - 15
Abstract: AIMS: The effects of radiotherapy on health-related quality of life (HRQOL) may influence decisions about adjuvant radiotherapy after breast-conserving surgery. We sought women's ratings of HRQOL during and after radiotherapy. MATERIALS AND METHODS: Women completed HRQOL measures before, during and after adjuvant radiotherapy for node-negative, hormone receptor-positive breast cancers that were less than 2 cm in size. Acute and late toxicities were rated by clinicians. RESULTS: There were 161 participants with a median age of 58 years (range 34-82). Mean scores for most aspects of HRQOL worsened only slightly during radiotherapy and improved to baseline levels or better within a few months. The symptoms rated as most distressing were: difficulty sleeping (29%), fatigue (23%), breast discolouration (21%), uncertainty about the future (18%), feeling sad or depressed (18%), feeling anxious or worried (19%). Most rated their experience as better (39%) or much better (28%) than expected. Grade 3 toxicities were rare (5% acute, 1% late) with no grade 4 toxicities. CONCLUSIONS: Radiotherapy was associated with transient and generally mild impairments in a few aspects of HRQOL. Concerns about adverse effects on HRQOL should not weigh heavily on decisions about adjuvant breast radiotherapy.
ISSN: 1433-2981
DOI: 10.1016/j.clon.2014.09.007
Journal Title: Clinical Oncology
Appears in Collections:Oncology / Cancer

Files in This Item:
There are no files associated with this item.

Items in the archive are protected by copyright, with all rights reserved, unless otherwise indicated.